

There’s a lot of snark, but the idea is this only inhibits pain in the peripheries, so it isn’t so psychoactively impacting. You don’t get sedated, the addiction profile is way less, and the LD50 means OD’ing is much harder. I’m sure there’s dependency potential, but it seems this is NOT recreational, which is huge, and if the sedation is less and you can take this and still function, it could be a game changer, allowing people impacted by chronic pain to re-enter the work force and have a better quality of life:
https://en.wikipedia.org/wiki/Suzetrigine https://pubmed.ncbi.nlm.nih.gov/39775738/
No, lots of people out there years out from an accident or injury can’t work and it leads to the opioid addiction cycle; having an option to control the pain and get people able to either work or do hobbies again, or do things with their families, would be huge.